Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
casd1CAS1 domain containing 1. (782 aa)    
Predicted Functional Partners:
siae
Sialic acid acetylesterase.
      
 0.773
LOC103474668
Sialidase 4.
      
 0.705
st8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family.
      
 0.650
St3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5; Belongs to the glycosyltransferase 29 family.
      
 0.594
LOC103459632
Cytidine monophospho-N-acetylneuraminic acid hydroxylase.
      
 0.586
ENSPREP00000005286
Uncharacterized protein; Belongs to the glycosyltransferase 29 family.
      
 0.579
LOC103481511
Uncharacterized protein; Belongs to the glycosyltransferase 29 family.
      
 0.579
LOC103481513
Uncharacterized protein; Belongs to the glycosyltransferase 29 family.
      
 0.579
LOC103460979
Coatomer protein complex, subunit gamma 2.
      
 0.561
st3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family.
      
 0.552
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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