dis3l2 protein (Poecilia reticulata) - STRING interaction network

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dis3l2

DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1060 aa)

Predicted Functional Partners:

exosc1

0.951

exosc10

0.947

ENSPREP00000026599

0.946

exosc2

0.945

exosc9

0.943

exosc4

0.941

mtrex

0.938

exosc6

0.938

exosc5

0.930

exosc3

0.925

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000026599	dis3l2	ENSPREP00000026599	ENSPREP00000003433	Exosome component 7.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	0.946
ENSPREP00000026599	exosc1	ENSPREP00000026599	ENSPREP00000000537	Exosome component 7.	Exosome component 1.	0.999
ENSPREP00000026599	exosc10	ENSPREP00000026599	ENSPREP00000024148	Exosome component 7.	Exosome component 10.	0.997
ENSPREP00000026599	exosc2	ENSPREP00000026599	ENSPREP00000021167	Exosome component 7.	Exosome component 2.	0.999
ENSPREP00000026599	exosc3	ENSPREP00000026599	ENSPREP00000016974	Exosome component 7.	Exosome component 3.	0.999
ENSPREP00000026599	exosc4	ENSPREP00000026599	ENSPREP00000014202	Exosome component 7.	Exosome component 4.	0.999
ENSPREP00000026599	exosc5	ENSPREP00000026599	ENSPREP00000026216	Exosome component 7.	Exosome component 5.	0.999
ENSPREP00000026599	exosc6	ENSPREP00000026599	ENSPREP00000028899	Exosome component 7.	Exosome component 6.	0.999
ENSPREP00000026599	exosc9	ENSPREP00000026599	ENSPREP00000002888	Exosome component 7.	Exosome component 9.	0.999
ENSPREP00000026599	mtrex	ENSPREP00000026599	ENSPREP00000004435	Exosome component 7.	Mtr4 exosome RNA helicase.	0.995
dis3l2	ENSPREP00000026599	ENSPREP00000003433	ENSPREP00000026599	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 7.	0.946
dis3l2	exosc1	ENSPREP00000003433	ENSPREP00000000537	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 1.	0.951
dis3l2	exosc10	ENSPREP00000003433	ENSPREP00000024148	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 10.	0.947
dis3l2	exosc2	ENSPREP00000003433	ENSPREP00000021167	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 2.	0.945
dis3l2	exosc3	ENSPREP00000003433	ENSPREP00000016974	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 3.	0.925
dis3l2	exosc4	ENSPREP00000003433	ENSPREP00000014202	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 4.	0.941
dis3l2	exosc5	ENSPREP00000003433	ENSPREP00000026216	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 5.	0.930
dis3l2	exosc6	ENSPREP00000003433	ENSPREP00000028899	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 6.	0.938
dis3l2	exosc9	ENSPREP00000003433	ENSPREP00000002888	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 9.	0.943
dis3l2	mtrex	ENSPREP00000003433	ENSPREP00000004435	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Mtr4 exosome RNA helicase.	0.938

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