dis3l2 protein (Poecilia reticulata) - STRING interaction network

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dis3l2

DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1060 aa)

Predicted Functional Partners:

exosc10

0.964

exosc1

0.961

exosc9

0.961

exosc8

0.958

exosc4

0.957

exosc3

0.957

exosc2

0.957

exosc5

0.957

hbs1l

0.949

exosc6

0.949

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dis3l2	exosc1	ENSPREP00000003433	ENSPREP00000000537	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 1.	0.961
dis3l2	exosc10	ENSPREP00000003433	ENSPREP00000024148	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 10.	0.964
dis3l2	exosc2	ENSPREP00000003433	ENSPREP00000021167	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 2.	0.957
dis3l2	exosc3	ENSPREP00000003433	ENSPREP00000016974	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 3.	0.957
dis3l2	exosc4	ENSPREP00000003433	ENSPREP00000014202	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 4.	0.957
dis3l2	exosc5	ENSPREP00000003433	ENSPREP00000026216	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 5.	0.957
dis3l2	exosc6	ENSPREP00000003433	ENSPREP00000028899	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 6.	0.949
dis3l2	exosc8	ENSPREP00000003433	ENSPREP00000017177	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 8.	0.958
dis3l2	exosc9	ENSPREP00000003433	ENSPREP00000002888	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 9.	0.961
dis3l2	hbs1l	ENSPREP00000003433	ENSPREP00000016672	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	HBS1-like translational GTPase.	0.949
exosc1	dis3l2	ENSPREP00000000537	ENSPREP00000003433	Exosome component 1.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	0.961
exosc1	exosc10	ENSPREP00000000537	ENSPREP00000024148	Exosome component 1.	Exosome component 10.	0.998
exosc1	exosc2	ENSPREP00000000537	ENSPREP00000021167	Exosome component 1.	Exosome component 2.	0.999
exosc1	exosc3	ENSPREP00000000537	ENSPREP00000016974	Exosome component 1.	Exosome component 3.	0.999
exosc1	exosc4	ENSPREP00000000537	ENSPREP00000014202	Exosome component 1.	Exosome component 4.	0.999
exosc1	exosc5	ENSPREP00000000537	ENSPREP00000026216	Exosome component 1.	Exosome component 5.	0.999
exosc1	exosc6	ENSPREP00000000537	ENSPREP00000028899	Exosome component 1.	Exosome component 6.	0.998
exosc1	exosc8	ENSPREP00000000537	ENSPREP00000017177	Exosome component 1.	Exosome component 8.	0.999
exosc1	exosc9	ENSPREP00000000537	ENSPREP00000002888	Exosome component 1.	Exosome component 9.	0.999
exosc1	hbs1l	ENSPREP00000000537	ENSPREP00000016672	Exosome component 1.	HBS1-like translational GTPase.	0.981

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