Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tcf25Transcription factor 25 (basic helix-loop-helix). (687 aa)    
Predicted Functional Partners:
ltn1
RING-type domain-containing protein.
   
 0.988
Nemf
Uncharacterized protein.
   
 0.981
ENSPREP00000007065
NFACT-R_1 domain-containing protein.
   
 0.981
rpl30
Ribosomal protein L30.
    
  0.915
RPL27A
Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family.
   
  0.912
rpl6
Ribosomal protein L6.
    
 0.907
def8
Differentially expressed in FDCP 8 homolog.
 
    
 0.902
rpl10
Ribosomal protein L10.
    
  0.895
rpl32
Ribosomal protein L32.
    
  0.895
rpl13a
Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
    
  0.895
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: medium (56%) [HD]