Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC103470395Solute carrier family 14 member 2. (512 aa)    
Predicted Functional Partners:
LOC103462946
V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.
    
   0.660
ace
Angiotensin-converting enzyme.
      
 0.602
aqp8
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.571
ENSPREP00000020277
RBR-type E3 ubiquitin transferase.
      
 0.556
medag
Uncharacterized protein.
      
 0.503
LOC103477611
Rh family, B glycoprotein (gene/pseudogene); Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
      
 0.503
rhag
Rh associated glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
      
 0.501
atp6v1f
V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
    
   0.500
tmem97
Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
    
 
 0.481
sord
Sorbitol dehydrogenase.
      
 0.473
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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