Tgfa protein (Poecilia reticulata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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co-expression

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[Homology]

Score

Tgfa

Transforming growth factor, alpha. (166 aa)

Predicted Functional Partners:

EGFR

0.969

egfr

0.969

LOC103461563

0.892

erbb3

0.892

erbb4

0.892

LOC103467364

0.892

ENSPREP00000034033

0.892

cnih1

0.880

ide

0.849

egf

0.791

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGFR	ENSPREP00000034033	ENSPREP00000015371	ENSPREP00000034033	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.900
EGFR	Tgfa	ENSPREP00000015371	ENSPREP00000003483	Receptor protein-tyrosine kinase.	Transforming growth factor, alpha.	0.969
EGFR	egf	ENSPREP00000015371	ENSPREP00000015161	Receptor protein-tyrosine kinase.	Epidermal growth factor.	0.937
EGFR	egfr	ENSPREP00000015371	ENSPREP00000025280	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.902
ENSPREP00000034033	EGFR	ENSPREP00000034033	ENSPREP00000015371	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.900
ENSPREP00000034033	LOC103461563	ENSPREP00000034033	ENSPREP00000018021	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.804
ENSPREP00000034033	LOC103467364	ENSPREP00000034033	ENSPREP00000030973	Uncharacterized protein.	Erb-b2 receptor tyrosine kinase 3b.	0.804
ENSPREP00000034033	Tgfa	ENSPREP00000034033	ENSPREP00000003483	Uncharacterized protein.	Transforming growth factor, alpha.	0.892
ENSPREP00000034033	egf	ENSPREP00000034033	ENSPREP00000015161	Uncharacterized protein.	Epidermal growth factor.	0.899
ENSPREP00000034033	egfr	ENSPREP00000034033	ENSPREP00000025280	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.900
ENSPREP00000034033	erbb3	ENSPREP00000034033	ENSPREP00000018666	Uncharacterized protein.	Protein kinase domain-containing protein.	0.804
ENSPREP00000034033	erbb4	ENSPREP00000034033	ENSPREP00000024887	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.804
LOC103461563	ENSPREP00000034033	ENSPREP00000018021	ENSPREP00000034033	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.804
LOC103461563	Tgfa	ENSPREP00000018021	ENSPREP00000003483	Receptor protein-tyrosine kinase.	Transforming growth factor, alpha.	0.892
LOC103461563	egf	ENSPREP00000018021	ENSPREP00000015161	Receptor protein-tyrosine kinase.	Epidermal growth factor.	0.842
LOC103461563	erbb4	ENSPREP00000018021	ENSPREP00000024887	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.901
LOC103467364	ENSPREP00000034033	ENSPREP00000030973	ENSPREP00000034033	Erb-b2 receptor tyrosine kinase 3b.	Uncharacterized protein.	0.804
LOC103467364	Tgfa	ENSPREP00000030973	ENSPREP00000003483	Erb-b2 receptor tyrosine kinase 3b.	Transforming growth factor, alpha.	0.892
LOC103467364	egf	ENSPREP00000030973	ENSPREP00000015161	Erb-b2 receptor tyrosine kinase 3b.	Epidermal growth factor.	0.842
LOC103467364	erbb3	ENSPREP00000030973	ENSPREP00000018666	Erb-b2 receptor tyrosine kinase 3b.	Protein kinase domain-containing protein.	0.902