STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
def8Differentially expressed in FDCP 8 homolog. (440 aa)    
Predicted Functional Partners:
pdcd5
Programmed cell death 5.
      
 0.681
mthfsd
Methenyltetrahydrofolate synthetase domain containing.
      
 0.681
ENSPREP00000002713
VWFA domain-containing protein.
 
      0.595
uvrag
UV radiation resistance associated gene.
    
 
 0.594
tcf25
Transcription factor 25 (basic helix-loop-helix).
 
    
 0.573
mvd
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
      
 0.549
samsn1
SAM domain, SH3 domain and nuclear localisation signals 1a.
   
  
 0.536
LOC103462573
Cytochrome b-245, alpha polypeptide.
      
 0.528
znf276
Zinc finger protein 276.
      
 0.522
mc1r
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
      
 0.519
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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