| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC103473119 | fdft1 | ENSPREP00000017837 | ENSPREP00000029902 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Farnesyl-diphosphate farnesyltransferase 1. | 0.977 |
| LOC103473119 | ggps1 | ENSPREP00000017837 | ENSPREP00000011880 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.702 |
| LOC103473119 | idi1 | ENSPREP00000017837 | ENSPREP00000009858 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Isopentenyl-diphosphate delta isomerase 1. | 0.978 |
| LOC103473119 | lss | ENSPREP00000017837 | ENSPREP00000001213 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.764 |
| LOC103473119 | mvd | ENSPREP00000017837 | ENSPREP00000003399 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.923 |
| LOC103473119 | ndufaf6 | ENSPREP00000017837 | ENSPREP00000027230 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | NADH:ubiquinone oxidoreductase complex assembly factor 6. | 0.663 |
| LOC103473119 | pdss1 | ENSPREP00000017837 | ENSPREP00000001393 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. | 0.567 |
| LOC103473119 | rusc2 | ENSPREP00000017837 | ENSPREP00000003575 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | RUN and SH3 domain containing 2. | 0.601 |
| ap4s1 | rusc2 | ENSPREP00000004754 | ENSPREP00000003575 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | RUN and SH3 domain containing 2. | 0.602 |
| coq2 | fdft1 | ENSPREP00000012075 | ENSPREP00000029902 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Farnesyl-diphosphate farnesyltransferase 1. | 0.727 |
| coq2 | ggps1 | ENSPREP00000012075 | ENSPREP00000011880 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.785 |
| coq2 | idi1 | ENSPREP00000012075 | ENSPREP00000009858 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Isopentenyl-diphosphate delta isomerase 1. | 0.884 |
| coq2 | lss | ENSPREP00000012075 | ENSPREP00000001213 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.687 |
| coq2 | ndufaf6 | ENSPREP00000012075 | ENSPREP00000027230 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NADH:ubiquinone oxidoreductase complex assembly factor 6. | 0.605 |
| coq2 | pdss1 | ENSPREP00000012075 | ENSPREP00000001393 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. | 0.991 |
| coq2 | rusc2 | ENSPREP00000012075 | ENSPREP00000003575 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | RUN and SH3 domain containing 2. | 0.607 |
| fdft1 | LOC103473119 | ENSPREP00000029902 | ENSPREP00000017837 | Farnesyl-diphosphate farnesyltransferase 1. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.977 |
| fdft1 | coq2 | ENSPREP00000029902 | ENSPREP00000012075 | Farnesyl-diphosphate farnesyltransferase 1. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.727 |
| fdft1 | ggps1 | ENSPREP00000029902 | ENSPREP00000011880 | Farnesyl-diphosphate farnesyltransferase 1. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.960 |
| fdft1 | idi1 | ENSPREP00000029902 | ENSPREP00000009858 | Farnesyl-diphosphate farnesyltransferase 1. | Isopentenyl-diphosphate delta isomerase 1. | 0.877 |