STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ldhdLactate dehydrogenase D. (496 aa)    
Predicted Functional Partners:
hagh
Hydroxyacylglutathione hydrolase.
    
 0.952
LOC103465809
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.948
ldhb
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.939
LOC103466147
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.939
LOC103462680
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.938
LOC103478109
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.938
LOC103466422
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.938
pc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.920
ENSPREP00000014189
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.919
pdha1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.919
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.