STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metMET proto-oncogene, receptor tyrosine kinase. (1439 aa)    
Predicted Functional Partners:
LOC103477907
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
   
 0.961
LOC103476312
Uncharacterized protein.
   
 0.961
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
   
 0.961
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.960
lrig1
Leucine-rich repeats and immunoglobulin-like domains 1.
    
 0.952
lrig2
Leucine-rich repeats and immunoglobulin-like domains 2.
    
 0.951
lrig3
Leucine-rich repeats and immunoglobulin-like domains 3.
    
 0.951
Tns1
Phosphatase tensin-type domain-containing protein.
   
 0.950
tns2
Tensin 2b.
   
 0.950
LOC103466881
Tensin 2a.
   
 0.950
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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