Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hook1Hook microtubule-tethering protein 1. (723 aa)    
Predicted Functional Partners:
aktip
Akt interacting protein.
   
 
 0.939
fam160a1
Family with sequence similarity 160 member A1a.
    
 
 0.763
LOC103480892
Uncharacterized protein.
    
 
 0.763
fam160a2
Family with sequence similarity 160 member A2.
    
 
 0.763
dctn1
Dynactin 1b.
    
 
 0.709
LOC103480555
Dynactin 1a.
    
 
 0.709
LOC103465118
Bicaudal D homolog 2 (Drosophila).
   
 
 0.681
BICD2
BICD cargo adaptor 2.
   
 
 0.681
mcm4
DNA helicase; Belongs to the MCM family.
   
 
 0.663
LOC103467950
Zgc:162200.
   
 
 0.655
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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