MBNL1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MBNL1

Muscleblind like splicing regulator 1. (391 aa)

Predicted Functional Partners:

u2af2

0.658

LOC103464518

0.657

tardbp

0.657

LOC103468782

0.597

lrp12

0.597

atxn2

0.585

sf3b3

0.533

LOC103478782

0.532

dph1

0.473

pabpn1

0.473

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464518	MBNL1	ENSPREP00000006319	ENSPREP00000003899	TAR DNA binding protein.	Muscleblind like splicing regulator 1.	0.657
LOC103464518	atxn2	ENSPREP00000006319	ENSPREP00000022113	TAR DNA binding protein.	Ataxin 2.	0.592
LOC103464518	pabpn1	ENSPREP00000006319	ENSPREP00000016786	TAR DNA binding protein.	Poly(A) binding protein, nuclear 1.	0.480
LOC103464518	sf3b3	ENSPREP00000006319	ENSPREP00000029104	TAR DNA binding protein.	Splicing factor 3b, subunit 3.	0.651
LOC103464518	tardbp	ENSPREP00000006319	ENSPREP00000023804	TAR DNA binding protein.	TAR DNA binding protein, like.	0.901
LOC103464518	u2af2	ENSPREP00000006319	ENSPREP00000012894	TAR DNA binding protein.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.782
LOC103468782	MBNL1	ENSPREP00000006236	ENSPREP00000003899	GIPC PDZ domain containing family, member 1.	Muscleblind like splicing regulator 1.	0.597
LOC103468782	atxn2	ENSPREP00000006236	ENSPREP00000022113	GIPC PDZ domain containing family, member 1.	Ataxin 2.	0.436
LOC103468782	lrp12	ENSPREP00000006236	ENSPREP00000023040	GIPC PDZ domain containing family, member 1.	Low density lipoprotein receptor-related protein 12.	0.623
LOC103468782	pabpn1	ENSPREP00000006236	ENSPREP00000016786	GIPC PDZ domain containing family, member 1.	Poly(A) binding protein, nuclear 1.	0.602
LOC103478782	MBNL1	ENSPREP00000026932	ENSPREP00000003899	SAC domain-containing protein.	Muscleblind like splicing regulator 1.	0.532
LOC103478782	sf3b3	ENSPREP00000026932	ENSPREP00000029104	SAC domain-containing protein.	Splicing factor 3b, subunit 3.	0.669
LOC103478782	u2af2	ENSPREP00000026932	ENSPREP00000012894	SAC domain-containing protein.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.495
MBNL1	LOC103464518	ENSPREP00000003899	ENSPREP00000006319	Muscleblind like splicing regulator 1.	TAR DNA binding protein.	0.657
MBNL1	LOC103468782	ENSPREP00000003899	ENSPREP00000006236	Muscleblind like splicing regulator 1.	GIPC PDZ domain containing family, member 1.	0.597
MBNL1	LOC103478782	ENSPREP00000003899	ENSPREP00000026932	Muscleblind like splicing regulator 1.	SAC domain-containing protein.	0.532
MBNL1	atxn2	ENSPREP00000003899	ENSPREP00000022113	Muscleblind like splicing regulator 1.	Ataxin 2.	0.585
MBNL1	dph1	ENSPREP00000003899	ENSPREP00000015308	Muscleblind like splicing regulator 1.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.473
MBNL1	lrp12	ENSPREP00000003899	ENSPREP00000023040	Muscleblind like splicing regulator 1.	Low density lipoprotein receptor-related protein 12.	0.597
MBNL1	pabpn1	ENSPREP00000003899	ENSPREP00000016786	Muscleblind like splicing regulator 1.	Poly(A) binding protein, nuclear 1.	0.473