Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
amnAmnion associated transmembrane protein. (498 aa)    
Predicted Functional Partners:
cubn
Cubilin (intrinsic factor-cobalamin receptor).
   
 0.993
cdcp2
CUB domain containing protein 2.
   
 0.941
ENSPREP00000017402
CUB domain-containing protein.
   
 0.941
LOC103470288
Transcobalamin II.
     
 0.856
pcolce2
Procollagen C-endopeptidase enhancer 2b.
   
 0.718
mfrp
Membrane frizzled-related protein.
   
 0.629
LOC103471060
Zgc:154142; Belongs to the peptidase S1 family.
   
 0.597
nrp1
Neuropilin; Belongs to the neuropilin family.
   
 0.597
LOC103479471
Neuropilin; Belongs to the neuropilin family.
   
 0.597
LOC103471399
Phosphoethanolamine methyltransferase.
      
 0.545
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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