STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clic4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (257 aa)    
Predicted Functional Partners:
ENSPREP00000002387
Uncharacterized protein.
    
 0.547
c1qtnf6
C1q and TNF related 6b.
      
 0.532
LOC103460462
Gamma-aminobutyric acid (GABA) A receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.532
atp6v0a2
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
      
 0.532
rsph3
Radial spoke head 3.
      
 0.525
slc12a4
Solute carrier family 12 member 4.
   
  
 0.524
gabra1
Gamma-aminobutyric acid (GABA) A receptor, alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.495
GRXCR2
Glutaredoxin and cysteine rich domain containing 2.
     
 0.485
atp6v1f
V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
      
 0.474
ENSPREP00000007772
Glutaredoxin and cysteine rich domain containing 1 b.
     
 0.402
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.