Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC103477101Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (536 aa)    
Predicted Functional Partners:
comt
Catechol-O-methyltransferase b.
     
 0.948
LOC103470503
Indoleamine 2,3-dioxygenase 1.
   
 
 0.936
LOC103476765
Uncharacterized protein.
   
 
 0.936
LOC103472946
Hydroxysteroid (17-beta) dehydrogenase 8.
   
 
 0.934
LOC103477226
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
  
 0.934
ENSPREP00000021856
UDP glucuronosyltransferase 1 family, polypeptide B1.
   
 0.928
ENSPREP00000021887
Uncharacterized protein.
   
 0.928
LOC103478848
UDP glucuronosyltransferase 1 family, polypeptide B3; Belongs to the UDP-glycosyltransferase family.
   
 0.928
LOC103474474
Transmembrane O-methyltransferase.
   
 
 0.925
LOC103469917
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.923
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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