Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSPREP00000004218Docking protein 2. (545 aa)    
Predicted Functional Partners:
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
   
 
 0.932
tmem38a
Transmembrane protein 38A.
    
   0.897
tie1
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1.
    
 0.872
kifbp
Kif1 binding protein.
    
   0.839
LOC103480775
Docking protein 1b.
   
 
 0.778
inpp5d
Inositol polyphosphate-5-phosphatase D.
   
 
 0.739
snx12
Fibronectin type-III domain-containing protein.
   
  
 0.699
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
  0.696
LOC103478918
Tyrosine-protein kinase.
   
 0.662
lck
Tyrosine-protein kinase.
   
 0.662
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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