Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
runx3Runt-related transcription factor. (405 aa)    
Predicted Functional Partners:
cbfb
Core-binding factor subunit beta.
    
 0.958
yap1
Yes-associated protein 1.
    
 0.833
stub1
STIP1 homology and U-Box containing protein 1.
    
 0.823
LOC103468460
E1A binding protein p300 b.
    
 0.811
LOC103482005
E1A binding protein p300 a.
    
 0.811
Tal1
BHLH domain-containing protein.
    
 0.783
LOC103479412
T-cell acute lymphocytic leukemia 1.
    
 0.783
ENSPREP00000004470
Uncharacterized protein.
    
 0.779
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.755
lmo2
LIM domain only 2 (rhombotin-like 1).
    
 0.751
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.