Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
prkd1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (909 aa)    
Predicted Functional Partners:
pkd1
Polycystic kidney disease 1a.
    
 
 0.750
CERT1
Ceramide transporter 1.
    
 0.521
LOC103473286
Ceramide transporter 1b.
    
 0.521
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
      
 0.518
LOC103471589
CD40 ligand; Belongs to the tumor necrosis factor family.
      
 0.508
LOC103460357
Uncharacterized protein.
    
 
 0.410
hspb8
Heat shock protein b8; Belongs to the small heat shock protein (HSP20) family.
    
 
 0.407
LOC103478931
Uncharacterized protein; Belongs to the peptidase C14A family.
      
 0.404
LOC103459939
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
      
 0.404
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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