| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC103458335 | coq3 | ENSPREP00000025325 | ENSPREP00000023351 | Coenzyme Q8A, genome duplicate b. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.906 |
| LOC103458335 | coq4 | ENSPREP00000025325 | ENSPREP00000022199 | Coenzyme Q8A, genome duplicate b. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.629 |
| LOC103458335 | coq5 | ENSPREP00000025325 | ENSPREP00000006253 | Coenzyme Q8A, genome duplicate b. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.820 |
| LOC103458335 | coq6 | ENSPREP00000025325 | ENSPREP00000015485 | Coenzyme Q8A, genome duplicate b. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.909 |
| LOC103458335 | coq7 | ENSPREP00000025325 | ENSPREP00000000666 | Coenzyme Q8A, genome duplicate b. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.844 |
| LOC103458335 | coq9 | ENSPREP00000025325 | ENSPREP00000004365 | Coenzyme Q8A, genome duplicate b. | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. | 0.929 |
| LOC103458335 | pdss1 | ENSPREP00000025325 | ENSPREP00000001393 | Coenzyme Q8A, genome duplicate b. | Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. | 0.506 |
| LOC103474848 | coq3 | ENSPREP00000011877 | ENSPREP00000023351 | Coenzyme Q8B. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.917 |
| LOC103474848 | coq4 | ENSPREP00000011877 | ENSPREP00000022199 | Coenzyme Q8B. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.819 |
| LOC103474848 | coq5 | ENSPREP00000011877 | ENSPREP00000006253 | Coenzyme Q8B. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.856 |
| LOC103474848 | coq6 | ENSPREP00000011877 | ENSPREP00000015485 | Coenzyme Q8B. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.987 |
| LOC103474848 | coq7 | ENSPREP00000011877 | ENSPREP00000000666 | Coenzyme Q8B. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.885 |
| LOC103474848 | coq9 | ENSPREP00000011877 | ENSPREP00000004365 | Coenzyme Q8B. | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. | 0.961 |
| LOC103474848 | pdss1 | ENSPREP00000011877 | ENSPREP00000001393 | Coenzyme Q8B. | Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. | 0.898 |
| coq3 | LOC103458335 | ENSPREP00000023351 | ENSPREP00000025325 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Coenzyme Q8A, genome duplicate b. | 0.906 |
| coq3 | LOC103474848 | ENSPREP00000023351 | ENSPREP00000011877 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Coenzyme Q8B. | 0.917 |
| coq3 | coq4 | ENSPREP00000023351 | ENSPREP00000022199 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.999 |
| coq3 | coq5 | ENSPREP00000023351 | ENSPREP00000006253 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.999 |
| coq3 | coq6 | ENSPREP00000023351 | ENSPREP00000015485 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.999 |
| coq3 | coq7 | ENSPREP00000023351 | ENSPREP00000000666 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.998 |