ap4m1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ap4m1

AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (442 aa)

Predicted Functional Partners:

ap4s1

0.996

ap4b1

0.996

ENSPREP00000021372

0.990

ap1g1

0.915

Ap4e1

0.904

LOC103478890

0.896

LOC103476383

0.868

ap1b1

0.868

gak

0.809

LOC103480134

0.765

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ap4e1	ENSPREP00000021372	ENSPREP00000021405	ENSPREP00000021372	Adaptor related protein complex 4 subunit epsilon 1.	AP4E_app_platf domain-containing protein.	0.900
Ap4e1	LOC103476383	ENSPREP00000021405	ENSPREP00000025820	Adaptor related protein complex 4 subunit epsilon 1.	AP complex subunit beta.	0.823
Ap4e1	LOC103480134	ENSPREP00000021405	ENSPREP00000004499	Adaptor related protein complex 4 subunit epsilon 1.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.662
Ap4e1	ap1b1	ENSPREP00000021405	ENSPREP00000032144	Adaptor related protein complex 4 subunit epsilon 1.	AP complex subunit beta.	0.823
Ap4e1	ap4b1	ENSPREP00000021405	ENSPREP00000008088	Adaptor related protein complex 4 subunit epsilon 1.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.990
Ap4e1	ap4m1	ENSPREP00000021405	ENSPREP00000004376	Adaptor related protein complex 4 subunit epsilon 1.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.904
Ap4e1	ap4s1	ENSPREP00000021405	ENSPREP00000004754	Adaptor related protein complex 4 subunit epsilon 1.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.989
Ap4e1	gak	ENSPREP00000021405	ENSPREP00000012671	Adaptor related protein complex 4 subunit epsilon 1.	Cyclin G associated kinase.	0.888
ENSPREP00000021372	Ap4e1	ENSPREP00000021372	ENSPREP00000021405	AP4E_app_platf domain-containing protein.	Adaptor related protein complex 4 subunit epsilon 1.	0.900
ENSPREP00000021372	LOC103476383	ENSPREP00000021372	ENSPREP00000025820	AP4E_app_platf domain-containing protein.	AP complex subunit beta.	0.823
ENSPREP00000021372	LOC103480134	ENSPREP00000021372	ENSPREP00000004499	AP4E_app_platf domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.662
ENSPREP00000021372	ap1b1	ENSPREP00000021372	ENSPREP00000032144	AP4E_app_platf domain-containing protein.	AP complex subunit beta.	0.823
ENSPREP00000021372	ap1g1	ENSPREP00000021372	ENSPREP00000034290	AP4E_app_platf domain-containing protein.	AP-1 complex subunit gamma.	0.459
ENSPREP00000021372	ap4b1	ENSPREP00000021372	ENSPREP00000008088	AP4E_app_platf domain-containing protein.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.999
ENSPREP00000021372	ap4m1	ENSPREP00000021372	ENSPREP00000004376	AP4E_app_platf domain-containing protein.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.990
ENSPREP00000021372	ap4s1	ENSPREP00000021372	ENSPREP00000004754	AP4E_app_platf domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.998
ENSPREP00000021372	gak	ENSPREP00000021372	ENSPREP00000012671	AP4E_app_platf domain-containing protein.	Cyclin G associated kinase.	0.888
LOC103476383	Ap4e1	ENSPREP00000025820	ENSPREP00000021405	AP complex subunit beta.	Adaptor related protein complex 4 subunit epsilon 1.	0.823
LOC103476383	ENSPREP00000021372	ENSPREP00000025820	ENSPREP00000021372	AP complex subunit beta.	AP4E_app_platf domain-containing protein.	0.823
LOC103476383	LOC103478890	ENSPREP00000025820	ENSPREP00000032499	AP complex subunit beta.	AP-1 complex subunit gamma.	0.929

page 1 of 5

Server load: low (16%) [HD]

Permalink

Network

Fusion

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Neighborhood

© STRING Consortium 2026

Credits

Access

Info

About