STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prkg2cGMP-dependent protein kinase. (792 aa)    
Predicted Functional Partners:
gucy1b1
Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 0.923
gucy1a1
Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 0.921
GUCY1A2
Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 0.921
LOC103476798
Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily.
  
  
 
0.901
ENSPREP00000030008
Si:dkey-121j17.5; Belongs to the protein kinase superfamily.
     
 
0.900
akap10
A kinase (PRKA) anchor protein 10.
   
 0.593
Cxcr5
Chemokine (C-X-C motif) receptor 5; Belongs to the G-protein coupled receptor 1 family.
    
 0.541
prkaca
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
0.530
LOC103468785
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
   
0.530
LOC103479663
Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.
   
0.530
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.