STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMEMembrane metalloendopeptidase. (770 aa)    
Predicted Functional Partners:
agt
Angiotensinogen; Belongs to the serpin family.
    
 0.850
ide
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
      
 0.663
dpp3
Dipeptidyl peptidase 3; Belongs to the peptidase M49 family.
      
 0.648
edn1
Endothelin 1.
     
 0.641
LOC103461698
Fibroblast activation protein, alpha; Belongs to the peptidase S9B family.
   
  
 0.615
LOC103474217
Uncharacterized protein; Belongs to the peptidase S9B family.
   
  
 0.615
plch1
Phosphoinositide phospholipase C.
      
 0.548
ace
Angiotensin-converting enzyme.
   
  
 0.540
prep
Prolyl endopeptidase.
   
  
 0.532
psen2
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
  
 0.524
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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