STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tnk2Tyrosine kinase, non-receptor, 2b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1200 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.921
CDC42
Cell division cycle 42.
    
 
 0.716
LOC103465423
Cell division cycle 42.
    
 
 0.716
nck2
Cytoplasmic protein.
    
 
 0.694
nck1
Cytoplasmic protein.
    
 
 0.694
ENSPREP00000009325
GRB2 related adaptor protein b.
    
 0.595
ENSPREP00000009358
Uncharacterized protein.
    
 0.595
grap2
GRB2 related adaptor protein 2a.
    
 0.595
LOC103469145
GRB2 related adaptor protein a.
    
 0.595
snx9
Sorting nexin 9b.
    
 
 0.578
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.