STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arrb2Arrestin, beta 2a. (418 aa)    
Predicted Functional Partners:
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.967
gak
Cyclin G associated kinase.
    
 0.942
kif3a
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 0.939
gpr161
G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family.
   
 0.930
ENSPREP00000019402
Protein kinase domain-containing protein.
    
 0.921
map2k4
Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.
    
 0.921
gli2
GLI family zinc finger 2a.
    
 0.905
gli1
GLI family zinc finger 1.
    
 0.905
grk7
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
   
 0.875
LOC103474448
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
   
 0.875
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.