STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
clcn6Chloride channel 6; Belongs to the chloride channel (TC 2.A.49) family. (862 aa)    
Predicted Functional Partners:
ostm1
Osteoclastogenesis associated transmembrane protein 1.
    
 0.972
med19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.657
prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast).
      
 0.647
gpaa1
Glycosylphosphatidylinositol anchor attachment 1.
   
  
 0.571
cln5
CLN5 intracellular trafficking protein.
      
 0.542
inpp5b
Inositol polyphosphate-5-phosphatase B.
   
  
 0.532
ocrl
OCRL inositol polyphosphate-5-phosphatase.
   
  
 0.532
clns1a
Chloride channel, nucleotide-sensitive, 1A.
      
 0.531
tepsin
TEPSIN adaptor related protein complex 4 accessory protein.
      
 0.529
mthfr
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
      
 0.522
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.