Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nit1Nitrilase 1. (318 aa)    
Predicted Functional Partners:
ndufa11
NADH:ubiquinone oxidoreductase subunit A11.
   
   0.905
pola2
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
      
 0.758
tdp2
Tyrosyl-DNA phosphodiesterase 2b.
      
 0.694
foxred1
FAD-dependent oxidoreductase domain containing 1.
      
 0.651
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
     
 0.629
rnls
Renalase, FAD-dependent amine oxidase.
      
 0.601
ENSPREP00000030964
Purkinje cell protein 4 like 1.
      
 0.590
srm
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
  
 
 0.576
sms
Spermine synthase.
  
 
 0.576
QPRT
Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
  
 
 0.573
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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