Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nek4NIMA-related kinase 4. (874 aa)    
Predicted Functional Partners:
CDC25B
Cell division cycle 25B.
   
 0.878
rpgrip1l
RPGRIP1 like.
   
 
 0.794
cmc2
COX assembly mitochondrial protein.
      
 0.758
LOC103480551
RPGR interacting protein 1.
    
 
 0.742
ttc21b
Tetratricopeptide repeat domain 21B.
    
 
 0.724
snrnp70
Small nuclear ribonucleoprotein 70 (U1).
      
 0.694
cep162
Uncharacterized protein.
    
   0.660
chek1
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
   
 0.649
rpgr
Uncharacterized protein.
    
 0.642
spata7
Uncharacterized protein.
   
 
 0.641
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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