STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhcr77-dehydrocholesterol reductase. (491 aa)    
Predicted Functional Partners:
sc5d
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.993
dhcr24
24-dehydrocholesterol reductase.
 
 
 0.978
LOC103472487
Cytochrome P450, family 51; Belongs to the cytochrome P450 family.
   
 0.944
sqle
Squalene epoxidase a.
   
 
 0.932
ch25h
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.926
LOC103466612
Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family.
   
 0.924
LOC103466611
Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family.
   
 0.924
LOC103466608
Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family.
   
 0.924
ENSPREP00000027667
Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family.
   
 0.924
LOC103479251
Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
   
 0.916
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.