STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103462238Matrix metallopeptidase 15b. (654 aa)    
Predicted Functional Partners:
LOC103468846
TIMP metallopeptidase inhibitor 2b.
   
 0.886
LOC103481516
TIMP metallopeptidase inhibitor 2a.
   
 0.852
adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1.
      
 0.646
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.640
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 1.
    
 0.610
LOC103462559
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
    
 0.551
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
    
 0.551
LOC103458626
Connexin 35.4.
      
 0.550
LOC103457247
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.550
LOC103474777
Matrix metallopeptidase 20b (enamelysin).
  
0.520
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.