STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
c5Anaphylatoxin-like domain-containing protein. (1413 aa)    
Predicted Functional Partners:
c6
Complement component 6.
   
 0.999
C8A
Complement C8 alpha chain.
   
 0.999
LOC103482421
Complement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family.
   
 0.999
c7
Complement component 7a.
   
 0.999
c9
Complement component 9.
   
 0.999
C5AR1
Complement C5a receptor 1.
    
 0.998
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.980
c3
Uncharacterized protein.
   
0.958
c8b
Complement component 8, beta polypeptide.
   
 0.953
LOC103478388
NTR domain-containing protein.
     
 
0.900
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.