STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000004672SH2 domain-containing protein. (141 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.956
cd79a
CD79a molecule, immunoglobulin-associated alpha.
   
 0.839
LOC103481840
Ig-like domain-containing protein.
   
 
 0.757
nck2
Cytoplasmic protein.
    
 0.722
nck1
Cytoplasmic protein.
    
 0.722
CD2AP
CD2 associated protein.
    
 0.701
sh3d21
SH3 domain containing 21.
    
 0.701
sh3kbp1
SH3-domain kinase binding protein 1.
    
 0.701
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.667
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.667
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.