STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sgtaSmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha. (359 aa)    
Predicted Functional Partners:
bag6
BCL2 associated athanogene 6.
   
 0.955
LOC103470505
Ubiquitin like 4A.
   
 0.955
get4
Guided entry of tail-anchored proteins factor 4.
   
 0.950
get3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
   
 0.937
Sec61b
Uncharacterized protein.
   
 0.889
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
   
 
 0.758
gosr2
Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
   
   0.752
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
  0.739
get1
Guided entry of tail-anchored proteins factor 1.
    
 0.732
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.731
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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