STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
p4hbProtein disulfide-isomerase. (509 aa)    
Predicted Functional Partners:
ero1a
Endoplasmic reticulum oxidoreductase alpha.
   
 0.985
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.985
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.952
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.929
LOC103479782
Calreticulin.
   
 0.895
LOC103464072
Calreticulin.
   
 0.895
mttp
Microsomal triglyceride transfer protein.
    
 0.863
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
 0.824
Ankrd45
ANK_REP_REGION domain-containing protein.
   
 0.822
p4ha3
Prolyl 4-hydroxylase, alpha polypeptide III.
   
 0.807
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.