STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
p4hbProtein disulfide-isomerase. (509 aa)    
Predicted Functional Partners:
ero1a
Endoplasmic reticulum oxidoreductase alpha.
   
 0.980
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.980
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.894
mttp
Microsomal triglyceride transfer protein.
   
 0.861
p4ha3
Prolyl 4-hydroxylase, alpha polypeptide III.
   
 0.838
Ankrd45
ANK_REP_REGION domain-containing protein.
   
 0.798
LOC103479782
Calreticulin.
   
 0.796
LOC103464072
Calreticulin.
   
 0.796
ppib
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.738
p4ha2
Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2.
   
 0.725
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.