Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lrrc45Leucine rich repeat containing 45. (674 aa)    
Predicted Functional Partners:
ENSPREP00000024682
KxDL motif containing 1.
    
  0.932
CEP164
Centrosomal protein 164.
   
 0.827
cntln
Centlein, centrosomal protein.
      
 0.798
cep83
Centrosomal protein 83.
    
 0.753
sclt1
Sodium channel and clathrin linker 1.
    
 0.737
fbf1
Uncharacterized protein.
   
  
 0.719
cep89
Centrosomal protein 89.
     
 0.718
crocc
Uncharacterized protein.
    
 
 0.678
armc8
Armadillo repeat containing 8.
      
 0.677
ENSPREP00000026574
ANK_REP_REGION domain-containing protein.
   
  0.653
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.