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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppp1r27Protein phosphatase 1, regulatory subunit 27b. (167 aa)    
Predicted Functional Partners:
ppp1cb
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.650
LOC103468963
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.650
ppp1cc
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.650
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.650
LOC103481373
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.650
LOC103462811
Protein disulfide-isomerase.
    
 0.576
LOC103476193
Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa.
     
 0.442
dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8.
   
 0.423
dhx34
DEAH (Asp-Glu-Ala-His) box polypeptide 34.
   
 0.423
PLK1
Serine/threonine-protein kinase PLK.
    
  0.417
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.