STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spire2Spire-type actin nucleation factor 2. (773 aa)    
Predicted Functional Partners:
LOC103470528
PDZ and LIM domain 2 (mystique).
    
 0.675
grap2
GRB2 related adaptor protein 2a.
   
 0.647
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.589
grb2
Growth factor receptor-bound protein 2b.
    
 0.539
Pacrg
PARK2 co-regulated.
    
 
 0.488
nck2
Cytoplasmic protein.
    
 0.472
nck1
Cytoplasmic protein.
    
 0.472
syk
Tyrosine-protein kinase.
   
 0.466
LOC103468233
Tyrosine-protein kinase.
   
 0.466
pik3r3
Uncharacterized protein.
    
 0.440
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.