STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SHISA6Shisa family member 6. (571 aa)    
Predicted Functional Partners:
LOC103472852
Calcium channel, voltage-dependent, gamma subunit 8a.
   
 
 0.666
LOC103478057
Calcium channel, voltage-dependent, gamma subunit 8b.
   
 
 0.666
LOC103466593
C2 calcium dependent domain containing 4A.
      
 0.627
LOC103479134
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 
 0.591
ENSPREP00000001193
Calcium voltage-gated channel auxiliary subunit gamma 7.
   
 
 0.587
LOC103469220
Calcium channel, voltage-dependent, gamma subunit 5b.
   
 
 0.587
spata20
Spermatogenesis associated 20.
      
 0.586
abhd6
Abhydrolase domain containing 6b.
     
 0.581
LOC103464284
Abhydrolase domain containing 6.
     
 0.581
spata18
Spermatogenesis associated 18.
      
 0.576
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.