STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Six3SIX homeobox 3a. (341 aa)    
Predicted Functional Partners:
wnt1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 
 0.724
ENSPREP00000014560
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.580
eya4
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.580
LOC103464861
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.580
eya1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.580
pax6
Paired box 6b.
   
 
 0.528
otx2
Orthodenticle homeobox 2b.
   
 
 0.520
VSX2
Visual system homeobox 2.
   
  
 0.517
gbx2
Gastrulation brain homeobox 2.
    
 
 0.442
sall2
Si:ch211-212k18.5.
   
 
 0.432
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.