Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dvl1Dishevelled segment polarity protein 1a. (653 aa)    
Predicted Functional Partners:
fzd10
Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.994
VANGL1
Vang-like protein.
    
 0.978
VANGL2
VANGL planar cell polarity protein 2.
    
 0.973
LOC103480354
Vang-like protein.
    
 0.973
LOC103456513
Uncharacterized protein.
   
0.967
AXIN2
Axin 2.
   
 0.967
LOC103469222
Axin 2 (conductin, axil).
   
0.967
axin1
Axin 1.
   
0.967
LOC103478532
Zgc:86598; Belongs to the protein kinase superfamily.
    
 0.962
daam2
Dishevelled associated activator of morphogenesis 2.
    
 0.962
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: medium (44%) [HD]