STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dcxrDicarbonyl/L-xylulose reductase. (224 aa)    
Predicted Functional Partners:
nudcd1
NudC domain containing 1.
    
   0.835
LOC103464679
Nuclear receptor coactivator 5.
      
 0.656
aqr
Aquarius intron-binding spliceosomal factor.
      
 0.604
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
      
 0.578
foxred1
FAD-dependent oxidoreductase domain containing 1.
      
 0.575
LOC103477555
RAB11a, member RAS oncogene family, like.
      
 0.568
sphk2
Sphingosine kinase 2.
    
   0.564
SPHK1
Sphingosine kinase 1.
    
   0.564
SPHK1-2
Sphingosine kinase 1.
    
   0.564
itpa
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
      
 0.535
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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