STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
g2e3G2/M-phase specific E3 ubiquitin protein ligase. (739 aa)    
Predicted Functional Partners:
wdr6
WD repeat domain 6.
    
   0.728
rbbp5
Retinoblastoma binding protein 5.
    
 0.652
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.629
dlgap5
Discs, large (Drosophila) homolog-associated protein 5.
   
  
 0.534
ENSPREP00000027387
PP1-binding domain-containing protein.
   
  
 0.532
cdca8
Cell division cycle associated 8.
   
 0.528
hykk
Hydroxylysine kinase, tandem duplicate 1.
      
 0.503
prim1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
  
 0.496
eed
Embryonic ectoderm development.
   
 0.490
ncapd2
Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
      
 0.488
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.