tsn protein (Poecilia reticulata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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gene neighborhood

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[Homology]

Score

tsn

Translin. (227 aa)

Predicted Functional Partners:

Tsnax

0.999

strap

0.930

LOC103463131

0.822

c1d

0.758

ttc4

0.728

amdhd2

0.721

naa40

0.666

LOC103472230

0.663

LOC103477773

0.663

LOC103477771

0.663

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103463131	tsn	ENSPREP00000033737	ENSPREP00000004979	Abnormal spindle microtubule assembly.	Translin.	0.822
LOC103472230	Tsnax	ENSPREP00000002849	ENSPREP00000012375	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Translin-associated factor X.	0.699
LOC103472230	tsn	ENSPREP00000002849	ENSPREP00000004979	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Translin.	0.663
LOC103477771	Tsnax	ENSPREP00000009729	ENSPREP00000012375	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Translin-associated factor X.	0.699
LOC103477771	tsn	ENSPREP00000009729	ENSPREP00000004979	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Translin.	0.663
LOC103477773	Tsnax	ENSPREP00000009674	ENSPREP00000012375	Argonaute RISC component 1; Belongs to the argonaute family.	Translin-associated factor X.	0.699
LOC103477773	tsn	ENSPREP00000009674	ENSPREP00000004979	Argonaute RISC component 1; Belongs to the argonaute family.	Translin.	0.663
Tsnax	LOC103472230	ENSPREP00000012375	ENSPREP00000002849	Translin-associated factor X.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.699
Tsnax	LOC103477771	ENSPREP00000012375	ENSPREP00000009729	Translin-associated factor X.	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.699
Tsnax	LOC103477773	ENSPREP00000012375	ENSPREP00000009674	Translin-associated factor X.	Argonaute RISC component 1; Belongs to the argonaute family.	0.699
Tsnax	c1d	ENSPREP00000012375	ENSPREP00000000988	Translin-associated factor X.	C1D nuclear receptor corepressor.	0.815
Tsnax	naa40	ENSPREP00000012375	ENSPREP00000001030	Translin-associated factor X.	N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae).	0.462
Tsnax	tsn	ENSPREP00000012375	ENSPREP00000004979	Translin-associated factor X.	Translin.	0.999
amdhd2	tsn	ENSPREP00000016567	ENSPREP00000004979	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family.	Translin.	0.721
c1d	Tsnax	ENSPREP00000000988	ENSPREP00000012375	C1D nuclear receptor corepressor.	Translin-associated factor X.	0.815
c1d	tsn	ENSPREP00000000988	ENSPREP00000004979	C1D nuclear receptor corepressor.	Translin.	0.758
naa40	Tsnax	ENSPREP00000001030	ENSPREP00000012375	N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae).	Translin-associated factor X.	0.462
naa40	tsn	ENSPREP00000001030	ENSPREP00000004979	N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae).	Translin.	0.666
strap	tsn	ENSPREP00000018096	ENSPREP00000004979	Serine/threonine kinase receptor associated protein.	Translin.	0.930
tsn	LOC103463131	ENSPREP00000004979	ENSPREP00000033737	Translin.	Abnormal spindle microtubule assembly.	0.822