Fras1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

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[Homology]

Score

Fras1

Uncharacterized protein. (288 aa)

Predicted Functional Partners:

frem2

0.969

LOC103474980

0.958

LOC103465492

0.922

itga8

0.910

itgb1

0.902

frem1

0.887

npnt

0.872

LOC103463284

0.869

frem3

0.810

LOC103480945

0.802

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Fras1	LOC103463284	ENSPREP00000005000	ENSPREP00000007870	Uncharacterized protein.	Fras1 related extracellular matrix 1b.	0.869
Fras1	LOC103465492	ENSPREP00000005000	ENSPREP00000030717	Uncharacterized protein.	Uncharacterized protein.	0.922
Fras1	LOC103474980	ENSPREP00000005000	ENSPREP00000019629	Uncharacterized protein.	FRAS1 related extracellular matrix 2b.	0.958
Fras1	LOC103480945	ENSPREP00000005000	ENSPREP00000022761	Uncharacterized protein.	Uncharacterized protein.	0.802
Fras1	frem1	ENSPREP00000005000	ENSPREP00000031492	Uncharacterized protein.	Fras1 related extracellular matrix 1a.	0.887
Fras1	frem2	ENSPREP00000005000	ENSPREP00000017967	Uncharacterized protein.	FRAS1 related extracellular matrix 2a.	0.969
Fras1	frem3	ENSPREP00000005000	ENSPREP00000034333	Uncharacterized protein.	Fras1 related extracellular matrix 3.	0.810
Fras1	itga8	ENSPREP00000005000	ENSPREP00000029861	Uncharacterized protein.	Integrin, alpha 8; Belongs to the integrin alpha chain family.	0.910
Fras1	itgb1	ENSPREP00000005000	ENSPREP00000008737	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.902
Fras1	npnt	ENSPREP00000005000	ENSPREP00000009090	Uncharacterized protein.	Nephronectin a.	0.872
LOC103463284	Fras1	ENSPREP00000007870	ENSPREP00000005000	Fras1 related extracellular matrix 1b.	Uncharacterized protein.	0.869
LOC103463284	LOC103465492	ENSPREP00000007870	ENSPREP00000030717	Fras1 related extracellular matrix 1b.	Uncharacterized protein.	0.503
LOC103463284	LOC103480945	ENSPREP00000007870	ENSPREP00000022761	Fras1 related extracellular matrix 1b.	Uncharacterized protein.	0.800
LOC103463284	itga8	ENSPREP00000007870	ENSPREP00000029861	Fras1 related extracellular matrix 1b.	Integrin, alpha 8; Belongs to the integrin alpha chain family.	0.908
LOC103463284	itgb1	ENSPREP00000007870	ENSPREP00000008737	Fras1 related extracellular matrix 1b.	Integrin beta; Belongs to the integrin beta chain family.	0.903
LOC103463284	npnt	ENSPREP00000007870	ENSPREP00000009090	Fras1 related extracellular matrix 1b.	Nephronectin a.	0.820
LOC103465492	Fras1	ENSPREP00000030717	ENSPREP00000005000	Uncharacterized protein.	Uncharacterized protein.	0.922
LOC103465492	LOC103463284	ENSPREP00000030717	ENSPREP00000007870	Uncharacterized protein.	Fras1 related extracellular matrix 1b.	0.503
LOC103465492	LOC103480945	ENSPREP00000030717	ENSPREP00000022761	Uncharacterized protein.	Uncharacterized protein.	0.409
LOC103465492	frem1	ENSPREP00000030717	ENSPREP00000031492	Uncharacterized protein.	Fras1 related extracellular matrix 1a.	0.503