Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aff1Uncharacterized protein. (1096 aa)    
Predicted Functional Partners:
eaf1
EAF domain-containing protein.
    
 0.995
Cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase).
    
 0.992
aff4
AF4/FMR2 family, member 4.
    
0.977
mllt3
MLLT3 super elongation complex subunit.
    
 0.955
mllt1
MLLT1 super elongation complex subunit a.
    
 0.955
ENSPREP00000012074
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.935
ccnt2
Cyclin T2; Belongs to the cyclin family.
   
 0.935
eaf2
ELL associated factor 2.
    
 0.889
LOC103462177
Uncharacterized protein.
    
 0.868
LOC103466632
Si:ch211-13k12.2.
    
 0.868
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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