STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103477201Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (538 aa)    
Predicted Functional Partners:
sftpb
Uncharacterized protein.
     
 
0.900
LOC103470281
Surfactant protein Bb.
     
 
0.900
galc
Galactosylceramidase b.
    
 
 0.856
naga
Alpha-galactosidase.
   
 0.839
gla
Alpha-galactosidase.
   
 0.839
arsa
Arylsulfatase A.
     
 0.800
Gm2a
GM2 ganglioside activator.
   
 
 0.760
ppt1
Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).
   
 
 0.718
LOC103468100
G protein-coupled receptor 37 like 1b.
     
 0.709
LOC103459425
G protein-coupled receptor 37b.
     
 0.709
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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