Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSPREP00000005025Prolyl endopeptidase like. (578 aa)    
Predicted Functional Partners:
slc3a1
Solute carrier family 3 member 1.
   
  
 0.902
alg14
ALG14 UDP-N-acetylglucosaminyltransferase subunit.
      
 0.685
surf2
Surfeit 2.
      
 0.683
dpagt1
Uncharacterized protein.
      
 0.679
cuedc2
CUE domain containing 2.
      
 0.670
plekhj1
Pleckstrin homology domain containing, family J member 1.
      
 0.655
CAMKMT
Calmodulin-lysine N-methyltransferase.
      
 0.654
ENSPREP00000004981
Uncharacterized protein.
      
 0.654
LOC103481621
Synaptotagmin XV.
      
 0.601
LOC103470517
Glutamine--fructose-6-phosphate transaminase 1.
   
  
 0.600
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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