itfg1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

itfg1

Integrin alpha FG-GAP repeat containing 1. (594 aa)

Predicted Functional Partners:

SOGA1

0.549

dennd5a

0.549

pomp

0.541

phkb

0.531

pdcd2

0.440

ruvbl2

0.416

LOC103466070

0.412

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103466070	itfg1	ENSPREP00000024318	ENSPREP00000005105	DENN/MADD domain containing 5B.	Integrin alpha FG-GAP repeat containing 1.	0.412
SOGA1	itfg1	ENSPREP00000019871	ENSPREP00000005105	Suppressor of glucose, autophagy associated 1.	Integrin alpha FG-GAP repeat containing 1.	0.549
dennd5a	itfg1	ENSPREP00000034082	ENSPREP00000005105	DENN/MADD domain containing 5A.	Integrin alpha FG-GAP repeat containing 1.	0.549
itfg1	LOC103466070	ENSPREP00000005105	ENSPREP00000024318	Integrin alpha FG-GAP repeat containing 1.	DENN/MADD domain containing 5B.	0.412
itfg1	SOGA1	ENSPREP00000005105	ENSPREP00000019871	Integrin alpha FG-GAP repeat containing 1.	Suppressor of glucose, autophagy associated 1.	0.549
itfg1	dennd5a	ENSPREP00000005105	ENSPREP00000034082	Integrin alpha FG-GAP repeat containing 1.	DENN/MADD domain containing 5A.	0.549
itfg1	pdcd2	ENSPREP00000005105	ENSPREP00000014853	Integrin alpha FG-GAP repeat containing 1.	Programmed cell death 2.	0.440
itfg1	phkb	ENSPREP00000005105	ENSPREP00000004907	Integrin alpha FG-GAP repeat containing 1.	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family.	0.531
itfg1	pomp	ENSPREP00000005105	ENSPREP00000016112	Integrin alpha FG-GAP repeat containing 1.	Proteasome maturation protein.	0.541
itfg1	ruvbl2	ENSPREP00000005105	ENSPREP00000012900	Integrin alpha FG-GAP repeat containing 1.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.416
pdcd2	itfg1	ENSPREP00000014853	ENSPREP00000005105	Programmed cell death 2.	Integrin alpha FG-GAP repeat containing 1.	0.440
phkb	itfg1	ENSPREP00000004907	ENSPREP00000005105	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family.	Integrin alpha FG-GAP repeat containing 1.	0.531
pomp	itfg1	ENSPREP00000016112	ENSPREP00000005105	Proteasome maturation protein.	Integrin alpha FG-GAP repeat containing 1.	0.541
ruvbl2	itfg1	ENSPREP00000012900	ENSPREP00000005105	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	Integrin alpha FG-GAP repeat containing 1.	0.416