Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fam72aFamily with sequence similarity 72 member B. (149 aa)    
Predicted Functional Partners:
ENSPREP00000015823
Rho-GAP domain-containing protein.
   
  
 0.721
arhgap11a
Rho GTPase activating protein 11A.
   
  
 0.721
ndc80
NDC80 kinetochore complex component.
   
    0.695
dlgap5
Discs, large (Drosophila) homolog-associated protein 5.
   
    0.685
ttk
Ttk protein kinase.
   
    0.666
LOC103470674
General transcription factor IIH subunit.
      
 0.649
LOC103480108
BolA family member 2; Belongs to the BolA/IbaG family.
      
 0.597
mtmr10
Myotubularin related protein 10.
      
 0.570
cdca8
Cell division cycle associated 8.
   
    0.548
pbk
PDZ binding kinase.
   
    0.548
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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