Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103459902Uncharacterized protein. (1039 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.934
LOC103472469
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 
0.923
sos1
Son of sevenless homolog 1 (Drosophila).
    
  0.916
sos2
Son of sevenless homolog 2 (Drosophila).
    
  0.916
SRC
Tyrosine-protein kinase.
    
 
0.911
LOC103467856
Tyrosine-protein kinase.
    
 
0.911
LOC103468765
Epithelial membrane protein 1.
     
  0.900
Kitlg
Kit ligand a.
    
  0.814
shc2
SHC (Src homology 2 domain containing) transforming protein 2.
   
 0.779
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
   
 0.779
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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