Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pxdnPeroxidasin. (1463 aa)    
Predicted Functional Partners:
gapdh
Glyceraldehyde-3-phosphate dehydrogenase.
      
 0.952
gapdhs
Glyceraldehyde-3-phosphate dehydrogenase.
      
 0.929
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
   
  
 0.922
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
      
 0.900
il10
Interleukin 10.
      
 0.883
becn1
Beclin 1, autophagy related.
      
 0.826
LOC103473229
Occludin a.
      
 0.797
mbp
Myelin basic protein b.
      
 0.793
eea1
Early endosome antigen 1.
      
 0.781
nes
IF rod domain-containing protein; Belongs to the intermediate filament family.
    
 0.759
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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