STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000005233Rap guanine nucleotide exchange factor (GEF) 5a. (540 aa)    
Predicted Functional Partners:
LOC103472577
Uncharacterized protein.
   
 
 0.591
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 
 0.591
mras
Muscle RAS oncogene homolog.
    
 0.582
ckap5
Cytoskeleton associated protein 5.
      
 0.577
slc35c1
Solute carrier family 35 member C1.
      
 0.523
LOC103467749
Uncharacterized protein.
    
 0.514
rap1b
Uncharacterized protein.
    
 0.514
LOC103464617
RAP1A, member of RAS oncogene family b.
    
 0.514
adam23
ADAM metallopeptidase domain 23.
      
 0.503
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1.
    
 
 0.486
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.